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Document type:
journal article 
Author(s):
Stoehr, GA; Rose, MA; Eber, SW; Heidemann, K; Schubert, R; Zielen, S 
Title:
Immunogenicity of sequential pneumococcal vaccination in subjects splenectomised for hereditary spherocytosis. 
Abstract:
Splenectomy predisposes for invasive pneumococcal disease. We investigated the immune response of splenectomised hereditary spherocytosis (HS) patients upon sequential pneumococcal vaccination. Thirty-nine HS-patients (2- to 18-year-old) had undergone near-total or total splenectomy. All received one dose of 7-valent pneumococcal conjugate vaccine (PCV-7) and 23-valent-pneumococcal-polysaccharide vaccine (PPV-23) 2 months apart. Pneumococcal antibodies against serotypes 5/6B/7/14/18C/19F/23F and...    »
 
Journal title abbreviation:
Br J Haematol 
Year:
2006 
Journal volume:
132 
Journal issue:
Pages contribution:
788-90 
Language:
eng 
Print-ISSN:
0007-1048 
TUM Institution:
Kinderklinik und Poliklinik