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Document type:
journal article 
Author(s):
Mautner, J; Jaffee, EM; Pardoll, DM 
Title:
Tumor-specific CD4+ T cells from a patient with renal cell carcinoma recognize diverse shared antigens. 
Abstract:
Murine models for immune-mediated tumor regression have defined an essential role for CD4+ T helper (Th) cells, but the contribution of these cells to antitumoral immune responses in humans remains poorly defined. Here, we investigated the Th cell response against the autologous tumor in a patient with metastasized renal cell carcinoma (RCC) exhibiting objective clinical response to immunotherapy. Peripheral blood T cells of the patient were repeatedly stimulated in vitro using either autologous...    »
 
Journal title abbreviation:
Int J Cancer 
Year:
2005 
Journal volume:
115 
Journal issue:
Pages contribution:
752-9 
Language:
eng 
Print-ISSN:
0020-7136 
TUM Institution:
Kinderklinik und Poliklinik