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Document type:
journal article 
Author(s):
Görlach, A; BelAiba, RS; Hess, J; Kietzmann, T 
Title:
Thrombin activates the p21-activated kinase in pulmonary artery smooth muscle cells. Role in tissue factor expression. 
Abstract:
The p21-activated serine/threonine kinases (PAK) play an important role in a variety of cellular functions. However, their role in the smooth muscle response to thrombin, which is activated upon vascular injury and promotes vascular remodelling processes, is not resolved. Here we investigated the role of PAK in thrombin signalling and regulation of tissue factor (TF), the activator of the extrinsic coagulation cascade, in pulmonary artery smooth muscle cells (PASMC), the main cell type responsib...    »
 
Journal title abbreviation:
Thromb Haemost 
Year:
2005 
Journal volume:
93 
Journal issue:
Pages contribution:
1168-75 
Language:
eng 
Print-ISSN:
0340-6245 
TUM Institution:
Klinik für Kinderkardiologie und angeborene Herzfehler