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Dokumenttyp:
journal article 
Autor(en):
Weber, MS; Starck, M; Wagenpfeil, S; Meinl, E; Hohlfeld, R; Farina, C 
Titel:
Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo. 
Abstract:
It is widely assumed that glatiramer acetate (GA), an approved agent for the immunomodulatory treatment of multiple sclerosis, acts primarily as an antigen for T lymphocytes. Recent studies, however, indicated that in vitro, GA directly inhibits dendritic cells, a rare but potent type of professional antigen-presenting cell (APC). To investigate whether these in vitro observations are relevant to the actions of GA in vivo, we studied the effects of GA on monocytes, the major type of circulating...    »
 
Zeitschriftentitel:
Brain 
Jahr:
2004 
Band / Volume:
127 
Heft / Issue:
Pt 6 
Seitenangaben Beitrag:
1370-8 
Sprache:
eng 
Print-ISSN:
0006-8950 
TUM Einrichtung:
r Medizinische Statistik und Epidemiologie