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Dokumenttyp:
journal article 
Autor(en):
Laaser, I; Theis, FJ; de Angelis, MH; Kolb, HJ; Adamski, J 
Titel:
Huge splicing frequency in human Y chromosomal UTY gene. 
Abstract:
Over 90% of human genes produce more than one mRNA by alternative splicing (AS). Human UTY (ubiquitously transcribed tetratricopeptide repeat protein on the chromosome Y) has six mRNA-transcripts. UTY is subject to interdisciplinary approaches such as Y chromosomal genetics or development of leukemia immunotherapy based on UTY-specific peptides. Investigating UTY expression in a normal and leukemic setting we discovered an exceptional splicing phenomenon fostering huge transcript diversity. Tran...    »
 
Zeitschriftentitel:
OMICS 
Jahr:
2011 
Band / Volume:
15 
Heft / Issue:
Seitenangaben Beitrag:
141-54 
Sprache:
eng 
Print-ISSN:
1536-2310 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik