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Dokumenttyp:
journal article 
Autor(en):
von Bubnoff, D; Scheler, M; Wilms, H; Wenzel, J; von Bubnoff, N; Häcker, G; Schultze, J; Popov, A; Racz, P; Bieber, T; Wickenhauser, C 
Titel:
Indoleamine 2,3-dioxygenase-expressing myeloid dendritic cells and macrophages in infectious and noninfectious cutaneous granulomas. 
Abstract:
The enzyme indoleamine 2,3-dioxygenase (IDO) degrades the essential amino acid tryptophan, and this degradation is an immunosuppressive mechanism that is mainly used by antigen-presenting cells. IDO-expressing dendritic cells and macrophages have previously been identified as components of lymph node granulomas after Listeria monocytogenes infection. In this study we undertook an analysis of IDO expression in granulomas of infectious and noninfectious origin in the human skin.Lesional skin biops...    »
 
Zeitschriftentitel:
J Am Acad Dermatol 
Jahr:
2011 
Band / Volume:
65 
Heft / Issue:
Seitenangaben Beitrag:
819-32 
Sprache:
eng 
Print-ISSN:
0190-9622 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik