Ritter, M;Gross, O;Kays, S;Ruland, J;Nimmerjahn, F;Saijo, S;Tschopp, J;Layland, LE;Prazeres da Costa, C
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses.
Proc Natl Acad Sci U S A
2010
107
47
20459-64

Mócsai, A;Ruland, J;Tybulewicz, VL
The SYK tyrosine kinase: a crucial player in diverse biological functions.
Nat Rev Immunol
2010
10
6
387-402

Poeck, H;Ruland, J
SYK kinase signaling and the NLRP3 inflammasome in antifungal immunity.
J Mol Med
2010
88
8
745-52

Schoenen, H;Bodendorfer, B;Hitchens, K;Manzanero, S;Werninghaus, K;Nimmerjahn, F;Agger, EM;Stenger, S;Andersen, P;Ruland, J;Brown, GD;Wells, C;Lang, R
Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.
J Immunol
2010
184
6
2756-60

Pechloff, K;Holch, J;Ferch, U;Schweneker, M;Brunner, K;Kremer, M;Sparwasser, T;Quintanilla-Martinez, L;Zimber-Strobl, U;Streubel, B;Gewies, A;Peschel, C;Ruland, J
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.
J Exp Med
2010
207
5
1031-44

Dorhoi, A;Desel, C;Yeremeev, V;Pradl, L;Brinkmann, V;Mollenkopf, HJ;Hanke, K;Gross, O;Ruland, J;Kaufmann, SH
The adaptor molecule CARD9 is essential for tuberculosis control.
J Exp Med
2010
207
4
777-92

Poeck, H;Ruland, J
ITAM receptor signaling and the NLRP3 inflammasome in antifungal immunity.
J Clin Immunol
2010
30
4
496-501

McAllister-Lucas, LM;Jin, X;Gu, S;Siu, K;McDonnell, S;Ruland, J;Delekta, PC;Van Beek, M;Lucas, PC
The CARMA3-Bcl10-MALT1 signalosome promotes angiotensin II-dependent vascular inflammation and atherogenesis.
J Biol Chem
2010
285
34
25880-4

Poeck, H;Bscheider, M;Gross, O;Finger, K;Roth, S;Rebsamen, M;Hannesschläger, N;Schlee, M;Rothenfusser, S;Barchet, W;Kato, H;Akira, S;Inoue, S;Endres, S;Peschel, C;Hartmann, G;Hornung, V;Ruland, J
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Nat Immunol
2010
11
1
63-9

Deenick, EK;Po, L;Chapatte, L;Murakami, K;Lu, YC;Elford, AR;Saibil, SD;Ruland, J;Gerondakis, S;Mak, TW;Ohashi, PS
c-Rel phenocopies PKCtheta but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance.
Eur J Immunol
2010
40
3
867-77