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Dokumenttyp:
journal article 
Autor(en):
Klemm, S; Ruland, J 
Titel:
Inflammatory signal transduction from the Fc epsilon RI to NF-kappaB. 
Abstract:
Mast cells are essential effector cells in IgE-associated immune responses. The major receptor for mast cell activation is the high affinity IgE receptor Fc epsilon RI. Fc epsilon RI crosslinking induces mast cell degranulation and de novo synthesis of potent proinflammatory mediators. Recent work identified Bcl10 and Malt1 as central regulators of a specific signaling pathway that controls NF-kappaB activation and proinflammatory cytokine production upon Fc epsilon RI ligation on mast cells. Bc...    »
 
Zeitschriftentitel:
Immunobiology 
Jahr:
2006 
Band / Volume:
211 
Heft / Issue:
10 
Seitenangaben Beitrag:
815-20 
Sprache:
eng 
Print-ISSN:
0171-2985 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik