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Dokumenttyp:
journal article 
Autor(en):
Decker, T; Hipp, S; Hahntow, I; Schneller, F; Peschel, C 
Titel:
Expression of cyclin E in resting and activated B-chronic lymphocytic leukaemia cells: cyclin E/cdk2 as a potential therapeutic target. 
Abstract:
Disease progression in B-cell chronic lymphocytic leukaemia (B-CLL) is determined by the interplay between proliferation kinetics in the proliferating compartment and cell death in the accumulating compartment. Improving our knowledge of cell cycle regulation in B-CLL cells might therefore be important for identifying therapeutic targets. Cyclin E was detected by Western blotting in purified B-CLL cells from peripheral blood samples of all 12 patient tested but not in normal peripheral blood B c...    »
 
Zeitschriftentitel:
Br J Haematol 
Jahr:
2004 
Band / Volume:
125 
Heft / Issue:
Seitenangaben Beitrag:
141-8 
Sprache:
eng 
Print-ISSN:
0007-1048 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik