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Dokumenttyp:
journal article 
Autor(en):
Ouyang, T; Bai, RY; Bassermann, F; von Klitzing, C; Klumpen, S; Miething, C; Morris, SW; Peschel, C; Duyster, J 
Titel:
Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA). 
Abstract:
Anaplastic large-cell lymphoma is a subtype of non-Hodgkin lymphomas characterized by the expression of CD30. More than half of these lymphomas carry a chromosomal translocation t(2; 5) leading to expression of the oncogenic tyrosine kinase nucleophosmin-anaplastic lymphoma kinase (NPM-ALK). NPM-ALK is capable of transforming fibroblasts and lymphocytes in vitro and of causing lymphomas in mice. Previously, we and others demonstrated phospholipase C-gamma and phosphatidylinositol 3-kinase as cru...    »
 
Zeitschriftentitel:
J Biol Chem 
Jahr:
2003 
Band / Volume:
278 
Heft / Issue:
32 
Seitenangaben Beitrag:
30028-36 
Sprache:
eng 
Print-ISSN:
0021-9258 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik