User: Guest  Login
Document type:
journal article 
Author(s):
Schneider, G; Krämer, OH 
Title:
NF?B/p53 crosstalk-a promising new therapeutic target. 
Abstract:
The transcription factors p53 and NF?B determine cellular fate and are involved in the pathogenesis of most-if not all-cancers. The crosstalk between these transcription factors becomes increasingly appreciated as an important mechanism operative during all stages of tumorigenesis, metastasis, and immunological surveillance. In this review, we summarize molecular mechanisms regulating cross-signaling between p53 and NF?B proteins and how dysregulated interactions between p53 and NF?B family memb...    »
 
Journal title abbreviation:
BBA - Rev Cancer 
Year:
2011 
Journal volume:
1815 
Journal issue:
Pages contribution:
90-103 
Language:
eng 
Print-ISSN:
0304-419X 
TUM Institution:
II. Medizinische Klinik und Poliklinik