User: Guest  Login
Document type:
journal article 
Author(s):
Pospisil, H; Herrmann, A; Butherus, K; Pirson, S; Reich, JG; Kemmner, W 
Title:
Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression. 
Abstract:
BACKGROUND: Splicing processes might play a major role in carcinogenesis and tumour progression. The Wnt pathway is of crucial relevance for cancer progression. Therefore we focussed on the Wnt/beta-catenin signalling pathway in order to validate the expression of sequences predicted as alternatively spliced by bioinformatic methods. Splice variants of its key molecules were selected, which may be critical components for the understanding of colorectal tumour progression and may have the potenti...    »
 
Journal title abbreviation:
BMC Genomics 
Year:
2006 
Journal volume:
Pages contribution:
148 
Language:
eng 
TUM Institution:
Kinderklinik und Poliklinik