Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Baust, H; Schoke, A; Brey, A; Gern, U; Los, M; Schmid, RM; Röttinger, EM; Seufferlein, T 
Titel:
Evidence for radiosensitizing by gliotoxin in HL-60 cells: implications for a role of NF-kappaB independent mechanisms. 
Abstract:
Radioresistance markedly impairs the efficacy of tumor radiotherapy and may involve antiapoptotic signal transduction pathways that prevent radiation-induced cell death. A common cellular response to genotoxic stress induced by radiation is the activation of the nuclear factor kappa B (NF-kappaB). NF-kappaB activation in turn can lead to an inhibition of radiation-induced apoptotic cell death. Thus, inhibition of NF-kappaB activation is commonly regarded as an important strategy to abolish radio...    »
 
Zeitschriftentitel:
Oncogene 
Jahr:
2003 
Band / Volume:
22 
Heft / Issue:
54 
Seitenangaben Beitrag:
8786-96 
Sprache:
eng 
Print-ISSN:
0950-9232 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik