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Dokumenttyp:
journal article 
Autor(en):
Langer, H; May, AE; Daub, K; Heinzmann, U; Lang, P; Schumm, M; Vestweber, D; Massberg, S; Schönberger, T; Pfisterer, I; Hatzopoulos, AK; Gawaz, M 
Titel:
Adherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitro. 
Abstract:
The homing and differentiation mechanisms of endothelial progenitor cells (EPCs) at sites of vascular lesions are unclear. To investigate whether platelets play a role in the recruitment and differentiation of EPCs, we made use of a robust mouse embryonic EPC (eEPC) line that reliably differentiates to a mature endothelial phenotype. We found that platelets stimulate chemotaxis and migration of these murine eEPCs. Further, the substantial adhesion of murine eEPCs on immobilized platelets that oc...    »
 
Zeitschriftentitel:
Circ Res 
Jahr:
2006 
Band / Volume:
98 
Heft / Issue:
Seitenangaben Beitrag:
e2-10 
Sprache:
eng 
Print-ISSN:
0009-7330 
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik