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Dokumenttyp:
journal article 
Autor(en):
Besta, F; Müller, I; Lorenz, M; Massberg, S; Bültmann, A; Cabeza, N; Richter, T; Kremmer, E; Nothdurfter, C; Brand, K; Gawaz, M 
Titel:
Reduced beta3-endonexin levels are associated with enhanced urokinase-type plasminogen activator receptor expression in ApoE-/- mice. 
Abstract:
Proteolysis of extracellular matrix components is required for cell migration occurring in atherosclerotic lesion formation. In the present study, gene expression of the urokinase plasmingen activator receptor (uPAR) and underlying mechanisms were analyzed during the development of atherosclerosis in the aorta of apolipoprotein E-deficient mice (apoE(-/-)). A significant increase of uPAR expression was detected in the atherosclerotic tissue with advancing plaque-dimension. As uPAR gene transcrip...    »
 
Zeitschriftentitel:
Thromb Res 
Jahr:
2004 
Band / Volume:
114 
Heft / Issue:
Seitenangaben Beitrag:
283-92 
Sprache:
eng 
Print-ISSN:
0049-3848 
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik; r Klinische Chemie und Pathobiochemie