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Dokumenttyp:
journal article 
Autor(en):
Steffens, M; Lamina, C; Illig, T; Bettecken, T; Vogler, R; Entz, P; Suk, EK; Toliat, MR; Klopp, N; Caliebe, A; König, IR; Köhler, K; Ludemann, J; Diaz Lacava, A; Fimmers, R; Lichtner, P; Ziegler, A; Wolf, A; Krawczak, M; N?rnberg, P; Hampe, J; Schreiber, S; Meitinger, T; Wichmann, HE; Roeder, K; Wienker, TF; Baur, MP 
Titel:
SNP-based analysis of genetic substructure in the German population. 
Abstract:
OBJECTIVE: To evaluate the relevance and necessity to account for the effects of population substructure on association studies under a case-control design in central Europe, we analysed three samples drawn from different geographic areas of Germany. Two of the three samples, POPGEN (n = 720) and SHIP (n = 709), are from north and north-east Germany, respectively, and one sample, KORA (n = 730), is from southern Germany. METHODS: Population genetic differentiation was measured by classical F-sta...    »
 
Zeitschriftentitel:
Hum Hered 
Jahr:
2006 
Band / Volume:
62 
Heft / Issue:
Seitenangaben Beitrag:
20-9 
Sprache:
eng 
Print-ISSN:
0001-5652 
TUM Einrichtung:
r Humangenetik