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Document type:
journal article 
Author(s):
Lehmann, MH; Walter, S; Ylisastigui, L; Striebel, F; Ovod, V; Geyer, M; Gluckman, JC; Erfle, V 
Title:
Extracellular HIV-1 Nef increases migration of monocytes. 
Abstract:
Infiltration of human immunodeficiency virus type 1 (HIV-1)-infected and uninfected monocytes/macrophages in organs and tissues is a general phenomenon observed in progression of acquired immunodeficiency syndrome (AIDS). HIV-1 protein Nef is considered as a progression factor in AIDS, and is released from HIV-1-infected cells. Here, we show that extracellular Nef increases migration of monocytes. This effect is (i) concentration-dependent, (ii) reaches the order of magnitude of that induced by...    »
 
Journal title abbreviation:
Exp Cell Res 
Year:
2006 
Journal volume:
312 
Journal issue:
18 
Pages contribution:
3659-68 
Language:
eng 
Print-ISSN:
0014-4827 
TUM Institution:
Institut für Virologie