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Document type:
journal article 
Author(s):
Bernlochner, I; Sibbing, D 
Title:
Thienopyridines and other ADP-receptor antagonists. 
Abstract:
Platelet P2Y12 receptor inhibition plays a pivotal role in preventing thrombotic vascular events in patients with ACS and in patients undergoing percutaneous coronary intervention (PCI). Among the P2Y12 receptor inhibitors, the group of thienopyridines include ticlopidine, clopidogrel and prasugrel, all of which are orally administered prodrugs leading to irreversible P2Y12 receptor inhibition. Non-thienopyridine derivatives including ticagrelor, cangrelor and elinogrel do not require metabolic...    »
 
Journal title abbreviation:
Handb Exp Pharmacol 
Year:
2012 
Journal issue:
210 
Pages contribution:
165-98 
Language:
eng 
Print-ISSN:
0171-2004 
TUM Institution:
Klinik für Herz- und Kreislauferkrankungen