Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Holzscheiter, L; Biermann, JC; Kotzsch, M; Prezas, P; Farthmann, J; Baretton, G; Luther, T; Tjan-Heijnen, VC; Talieri, M; Schmitt, M; Sweep, FC; Span, PN; Magdolen, V 
Titel:
Quantitative reverse transcription-PCR assay for detection of mRNA encoding full-length human tissue kallikrein 7: prognostic relevance of KLK7 mRNA expression in breast cancer. 
Abstract:
BACKGROUND: The human tissue kallikrein gene family (KLK1 to KLK15) encodes a group of 15 serine proteases (hK1 to hK15), several of which have been implicated in cancer-related processes. METHODS: We established a specific quantitative reverse transcription-PCR assay for full-length KLK7 mRNA that excluded amplification of the exon 2 deletion splice variant (the latter does not encode a functional protease), and evaluated full-length KLK7 mRNA expression [normalized to human glucose-6-phosphate...    »
 
Zeitschriftentitel:
Clin Chem 
Jahr:
2006 
Band / Volume:
52 
Heft / Issue:
Seitenangaben Beitrag:
1070-9 
Sprache:
eng 
Print-ISSN:
0009-9147 
TUM Einrichtung:
Frauenklinik und Poliklinik