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Dokumenttyp:
journal article 
Autor(en):
Martens, JW; Nimmrich, I; Koenig, T; Look, MP; Harbeck, N; Model, F; Kluth, A; Bolt-de Vries, J; Sieuwerts, AM; Portengen, H; Meijer-Van Gelder, ME; Piepenbrock, C; Olek, A; Höfler, H; Kiechle, M; Klijn, JG; Schmitt, M; Maier, S; Foekens, JA 
Titel:
Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer. 
Abstract:
To understand the biological basis of resistance to endocrine therapy is of utmost importance in patients with steroid hormone receptor-positive breast cancer. Not only will this allow us prediction of therapy success, it may also lead to novel therapies for patients resistant to current endocrine therapy. DNA methylation in the promoter regions of genes is a prominent epigenetic gene silencing mechanism that contributes to breast cancer biology. In the current study, we investigated whether pro...    »
 
Zeitschriftentitel:
Cancer Res 
Jahr:
2005 
Band / Volume:
65 
Heft / Issue:
10 
Seitenangaben Beitrag:
4101-17 
Sprache:
eng 
Print-ISSN:
0008-5472 
TUM Einrichtung:
Frauenklinik und Poliklinik; r Allgemeine Pathologie und pathologische Anatomie