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Dokumenttyp:
journal article 
Autor(en):
Magdolen, U; Schroeck, F; Creutzburg, S; Schmitt, M; Magdolen, V 
Titel:
Non-muscle alpha-actinin-4 interacts with plasminogen activator inhibitor type-1 (PAI-1). 
Abstract:
PAI-1 modulates many biological processes involving fibrinolysis, cell migration or tissue remodelling. In addition to inhibiting serine proteases (mainly tPA and uPA), PAI-1 interacts with vitronectin (Vn), fibrin or alpha(1)-acid glycoprotein, interactions which are important for PAI-1-mediated effects in inflammation, tumor invasion and metastasis. To further identify proteins interacting with PAI-1, the yeast two-hybrid strategy was employed. Screening of a human placenta cDNA library identi...    »
 
Zeitschriftentitel:
Biol Chem 
Jahr:
2004 
Band / Volume:
385 
Heft / Issue:
Seitenangaben Beitrag:
801-8 
Sprache:
eng 
Print-ISSN:
1431-6730 
TUM Einrichtung:
Frauenklinik und Poliklinik