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Document type:
journal article 
Author(s):
Pantel, K; Müller, V; Auer, M; Nusser, N; Harbeck, N; Braun, S 
Title:
Detection and clinical implications of early systemic tumor cell dissemination in breast cancer. 
Abstract:
Blood-borne distant metastasis is the leading cause of cancer-related death in breast cancer. The onset of this fundamental process can now be assessed in cancer patients using ultrasensitive immunocytochemical and molecular assays able to detect even single metastatic cells. Analyses of bone marrow (BM) samples show that disseminated cells are present in 20-40% of primary breast cancer patients without any clinical or histopathological signs of metastasis. The common homing of circulating breas...    »
 
Journal title abbreviation:
Clin Cancer Res 
Year:
2003 
Journal volume:
Journal issue:
17 
Pages contribution:
6326-34 
Language:
eng 
Print-ISSN:
1078-0432 
TUM Institution:
Frauenklinik und Poliklinik