User: Guest  Login
Document type:
journal article 
Author(s):
Bader, BL; Smyth, N; Nedbal, S; Miosge, N; Baranowsky, A; Mokkapati, S; Murshed, M; Nischt, R 
Title:
Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice. 
Abstract:
Nidogen 1 and 2 are basement membrane glycoproteins, and previous biochemical and functional studies indicate that they may play a crucial role in basement membrane assembly. While they show a divergent expression pattern in certain adult tissues, both have a similar distribution during development. Gene knockout studies in mice demonstrated that the loss of either isoform has no effect on basement membrane formation and organ development, suggesting complementary functions. Here, we show that t...    »
 
Journal title abbreviation:
Mol Cell Biol 
Year:
2005 
Journal volume:
25 
Journal issue:
15 
Pages contribution:
6846-56 
Language:
eng 
Print-ISSN:
0270-7306 
TUM Institution:
hrungsmedizin