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Document type:
journal article 
Author(s):
Sengenes, C; Bouloumie, A; Hauner, H; Berlan, M; Busse, R; Lafontan, M; Galitzky, J 
Title:
Involvement of a cGMP-dependent pathway in the natriuretic peptide-mediated hormone-sensitive lipase phosphorylation in human adipocytes. 
Abstract:
Our previous studies have demonstrated that natriuretic peptides (NPs), peptide hormones with natriuretic, diuretic, and vasodilating properties, exert a potent control on the lipolysis in human adipocytes via the activation of the type A guanylyl cyclase receptor (1, 2). In the current study we investigated the intracellular mechanisms involved in the NP-stimulated lipolytic effect in human preadipocytes and adipocytes. We demonstrate that the atrial NP (ANP)-induced lipolysis in human adipocyt...    »
 
Journal title abbreviation:
J Biol Chem 
Year:
2003 
Journal volume:
278 
Journal issue:
49 
Pages contribution:
48617-26 
Language:
eng 
Print-ISSN:
0021-9258 
TUM Institution:
hrungsmedizin