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Document type:
journal article 
Author(s):
Giovannetti, A; Mazzetta, F; Cavani, A; Pennino, D; Caprini, E; Ortona, E; Donato, G; Rosato, E; Salsano, F; Pierdominici, M 
Title:
Skewed T-cell receptor variable ? repertoire and massive T-cell activation in idiopathic orofacial granulomatosis. 
Abstract:
Orofacial granulomatosis (OFG) is a clinicopathologic entity describing oral lesions with noncaseating granulomas including a spectrum of diseases such as the Melkersson-Rosenthal syndrome. The involvement of abnormal T-cell responses has been suggested in the pathogenesis of OFG although few and contrasting data are currently available on this issue. In a patient with OFG, we observed virtually complete CD4 and CD8 T-cell receptor (TCR) ?-chain variable region (BV) repertoires at the lesion lev...    »
 
Journal title abbreviation:
Int J Immunopathol Pharmacol 
Year:
2012 
Journal volume:
25 
Journal issue:
Pages contribution:
503-11 
Language:
eng 
Print-ISSN:
0394-6320 
TUM Institution:
r Molekulare Allergologie und Umweltforschung