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Document type:
journal article 
Author(s):
Schmidt-Weber, CB 
Title:
Anti-IL-4 as a new strategy in allergy. 
Abstract:
Allergic diseases are characterized by an overreaction characterized by Th2-type cell response, and as a consequence, an IgE-switched B cell immunity. Obviously, type-2 cytokines (IL-4, IL-5, IL-9, IL-13) and particularly IL-4 have been identified as potential targets for allergy treatment. While initial experiences using anti-IL-4 principles in asthma were rather ambiguous, more recent studies using an IL-4 mute in blocking the IL-4 and IL-13 receptor have shown promising results. Furthermore,...    »
 
Journal title abbreviation:
Chem Immunol Allergy 
Year:
2012 
Journal volume:
96 
Pages contribution:
120-5 
Language:
eng 
Print-ISSN:
1660-2242 
TUM Institution:
r Molekulare Allergologie und Umweltforschung