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Dokumenttyp:
journal article 
Autor(en):
Verhagen, J; Akdis, M; Traidl-Hoffmann, C; Schmid-Grendelmeier, P; Hijnen, D; Knol, EF; Behrendt, H; Blaser, K; Akdis, CA 
Titel:
Absence of T-regulatory cell expression and function in atopic dermatitis skin. 
Abstract:
BACKGROUND: The role of regulatory T cells has been widely reported in the suppression of T-cell activation. A dysfunction in CD4(+)CD25(+) T-regulatory cell-specific transcription factor FoxP3 leads to immune dysregulation, polyendocrinopathy, enteropathy X-linked syndrome, often associated with atopic dermatitis. Increasing the number and activity of regulatory T cells in affected organs has been suggested as a remedy in various inflammatory diseases, including allergy. OBJECTIVE: To determine...    »
 
Zeitschriftentitel:
J Allergy Clin Immunol 
Jahr:
2006 
Band / Volume:
117 
Heft / Issue:
Seitenangaben Beitrag:
176-83 
Sprache:
eng 
Print-ISSN:
0091-6749 
TUM Einrichtung:
r Dermatologie und Allergologie