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Dokumenttyp:
journal article 
Autor(en):
Novak, N; Kruse, S; Potreck, J; Maintz, L; Jenneck, C; Weidinger, S; Fimmers, R; Bieber, T 
Titel:
Single nucleotide polymorphisms of the IL18 gene are associated with atopic eczema. 
Abstract:
BACKGROUND: Human IL-18 is an inflammatory cytokine that plays a role in atopic diseases, such as atopic eczema (AE), by enhancing IL-4 and IL-13 production and stimulating the synthesis of IgE. OBJECTIVE: To evaluate associations of polymorphisms in the IL18 gene on chromosome 11q22 with AE, we performed genotyping for single nucleotide polymorphisms (SNPs) in the IL18 gene in 225 patients with AE and 175 healthy control volunteers. METHODS: Genotyping was performed by means of restriction frag...    »
 
Zeitschriftentitel:
J Allergy Clin Immunol 
Jahr:
2005 
Band / Volume:
115 
Heft / Issue:
Seitenangaben Beitrag:
828-33 
Sprache:
eng 
Print-ISSN:
0091-6749 
TUM Einrichtung:
r Dermatologie und Allergologie