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Dokumenttyp:
journal article 
Autor(en):
Weidinger, S; Klopp, N; Rümmler, L; Wagenpfeil, S; Baurecht, HJ; Gauger, A; Darsow, U; Jakob, T; Novak, N; Schäfer, T; Heinrich, J; Behrendt, H; Wichmann, HE; Ring, J; Illig, T 
Titel:
Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults. 
Abstract:
BACKGROUND: Influences of microbial pathogens are crucial for the maturation of the immune system. Caspase-recruitment domain containing protein 15 (CARD15) is a cytosolic receptor involved in bacterial recognition by antigen-presenting cells. CARD15 polymorphisms have been associated with Crohn's disease. Recently, associations with atopic phenotypes have been reported in children. OBJECTIVE: Within a large population of German adults (n=1875), we evaluated eight CARD15 polymorphisms for associ...    »
 
Zeitschriftentitel:
Clin Exp Allergy 
Jahr:
2005 
Band / Volume:
35 
Heft / Issue:
Seitenangaben Beitrag:
866-72 
Sprache:
eng 
Print-ISSN:
0954-7894 
TUM Einrichtung:
r Dermatologie und Allergologie; r Medizinische Statistik und Epidemiologie