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Dokumenttyp:
journal article 
Autor(en):
Beer, AJ; Haubner, R; Goebel, M; Luderschmidt, S; Spilker, ME; Wester, HJ; Weber, WA; Schwaiger, M 
Titel:
Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients. 
Abstract:
(18)F-Galacto-RGD has been developed for PET of alpha(v)beta(3) integrin expression, a receptor involved in, for example, angiogenesis and metastasis. Our aim was to study the kinetics and biodistribution of (18)F-Galacto-RGD in cancer patients. METHODS: Nineteen patients with metastases of malignant melanoma (n = 7), sarcomas (n = 10), or osseous metastases (n = 2) were examined. After injection of 133-200 MBq (18)F-Galacto-RGD, 3 consecutive emission scans from the pelvis to the thorax or dyna...    »
 
Zeitschriftentitel:
J Nucl Med 
Jahr:
2005 
Band / Volume:
46 
Heft / Issue:
Seitenangaben Beitrag:
1333-41 
Sprache:
eng 
Print-ISSN:
0161-5505 
TUM Einrichtung:
r Radiologie; dische Klinik und Poliklinik; r Dermatologie und Allergologie; Nuklearmedizinische Klinik und Poliklinik