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Dokumenttyp:
journal article 
Autor(en):
Alessandrini, F; Pfister, S; Kremmer, E; Gerber, JK; Ring, J; Behrendt, H 
Titel:
Alterations of glucosylceramide-beta-glucosidase levels in the skin of patients with psoriasis vulgaris. 
Abstract:
Hydrolysis of glucosylceramides by the enzyme glucosylceramide-beta-glucosidase (GlcCer'ase) results in ceramide, a critical component of the intercellular lamellae that mediates the epidermal permeability barrier. A disturbance of ceramide formation is supposed to influence the transepidermal water loss in common skin diseases like atopic eczema or psoriasis. The aim of this study was to investigate whether GlcCer'ase levels were altered in the skin of subjects with psoriasis vulgaris. Skin pun...    »
 
Zeitschriftentitel:
J Invest Dermatol 
Jahr:
2004 
Band / Volume:
123 
Heft / Issue:
Seitenangaben Beitrag:
1030-6 
Sprache:
eng 
Print-ISSN:
0022-202X 
TUM Einrichtung:
r Dermatologie und Allergologie