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Dokumenttyp:
journal article 
Autor(en):
Meineke, V; Müller, K; Ridi, R; Cordes, N; Köhn, FM; Mayerhofer, A; Ring, J; van Beuningen, D 
Titel:
Development and evaluation of a skin organ model for the analysis of radiation effects. 
Abstract:
BACKGROUND AND PURPOSE: The reaction of tissues to ionizing radiation involves alterations in cell-cell and cell-matrix interactions mediated by cellular adhesion molecules. The aim of this study was to develop and evaluate an artificial skin organ model for the analysis of radiation effects. MATERIAL AND METHODS: A human co-culture system consisting of the spontaneously immortalized keratinocyte cell line HaCaT and primary HDFa fibroblasts embedded into a collagen sponge was established. This s...    »
 
Zeitschriftentitel:
Strahlenther Onkol 
Jahr:
2004 
Band / Volume:
180 
Heft / Issue:
Seitenangaben Beitrag:
102-8 
Sprache:
eng 
Print-ISSN:
0179-7158 
TUM Einrichtung:
r Dermatologie und Allergologie