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Dokumenttyp:
journal article 
Autor(en):
Ehnert, S; Schyschka, L; Noss, A; Knobeloch, D; Kleeff, J; Büchler, P; Gillen, S; Stöckle, U; Burkhart, J; Fabian, E; Nussler, AK 
Titel:
Further characterization of autologous NeoHepatocytes for in vitro toxicity testing. 
Abstract:
Gold standard for in vitro toxicity tests and drug screenings is primary human hepatocytes (hHeps). Because of their limited availability efforts have been made to provide alternatives, e.g., monocyte-derived NeoHepatocytes. In the past years it has been critically discussed if gaining hepatocyte features is associated with trans-differentiation of monocytes or their activation towards a macrophage phenotype. Generating NeoHepatocytes in the presence of six different human AB sera, fetal calf se...    »
 
Zeitschriftentitel:
Toxicol In Vitro 
Jahr:
2011 
Band / Volume:
25 
Heft / Issue:
Seitenangaben Beitrag:
1203-8 
Sprache:
eng 
Print-ISSN:
0887-2333 
TUM Einrichtung:
r Unfallchirurgie; Chirurgiesche Klinik und Poliklinik