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Dokumenttyp:
journal article 
Autor(en):
Verbeke, P; Welter-Stahl, L; Ying, S; Hansen, J; Häcker, G; Darville, T; Ojcius, DM 
Titel:
Recruitment of BAD by the Chlamydia trachomatis vacuole correlates with host-cell survival. 
Abstract:
Chlamydiae replicate intracellularly in a vacuole called an inclusion. Chlamydial-infected host cells are protected from mitochondrion-dependent apoptosis, partly due to degradation of BH3-only proteins. The host-cell adapter protein 14-3-3beta can interact with host-cell apoptotic signaling pathways in a phosphorylation-dependent manner. In Chlamydia trachomatis-infected cells, 14-3-3beta co-localizes to the inclusion via direct interaction with a C. trachomatis-encoded inclusion membrane prote...    »
 
Zeitschriftentitel:
PLoS Pathog 
Jahr:
2006 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e45 
Sprache:
eng 
Print-ISSN:
1553-7366 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene