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Document type:
journal article 
Author(s):
Kauer, WK; Stein, HJ 
Title:
Bile reflux in the constellation of gastroesophageal reflux disease. 
Abstract:
Gastric acid and bile acids are a particularly noxious combination when they interact with the mucosa of the upper intestinal tract. There is a critical pH range, between 3 and 6, in which bile acids exist in their soluble, un-ionized form, can penetrate cell membranes, and accumulate within mucosal cells. At a lower pH, bile acids are precipitated, and at a higher pH, bile acids exist in their noninjurious ionized form. Experimental, clinical, and immunohistochemical studies show that acid and...    »
 
Journal title abbreviation:
Thorac Surg Clin 
Year:
2005 
Journal volume:
15 
Journal issue:
Pages contribution:
335-40 
Language:
eng 
Print-ISSN:
1547-4127 
TUM Institution:
Chirurgiesche Klinik und Poliklinik