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Dokumenttyp:
journal article 
Autor(en):
Buras, JA; Holzmann, B; Sitkovsky, M 
Titel:
Animal models of sepsis: setting the stage. 
Abstract:
Sepsis is a state of disrupted inflammatory homeostasis that is often initiated by infection. The development and progression of sepsis is multi-factorial, and affects the cardiovascular, immunological and endocrine systems of the body. The complexity of sepsis makes the clinical study of sepsis and sepsis therapeutics difficult. Animal models have been developed in an effort to create reproducible systems for studying sepsis pathogenesis and preliminary testing of potential therapeutic agents....    »
 
Zeitschriftentitel:
Nat Rev Drug Discov 
Jahr:
2005 
Band / Volume:
Heft / Issue:
10 
Seitenangaben Beitrag:
854-65 
Sprache:
eng 
Print-ISSN:
1474-1776 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik