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Dokumenttyp:
journal article 
Autor(en):
Beierlein, W; Scheule, AM; Dietrich, W; Ziemer, G 
Titel:
Forty years of clinical aprotinin use: A review of 124 hypersensitivity reactions 
Abstract:
Since its clinical introduction, the anaphylactic potential of aprotinin has been a major concern. World wide, its use is expanding so there is an increased chance that patients have reexposure from various sources. The risk of anaphylaxis is approximately 2.8% in reexposed patients. From 1963 to 2003, 124 cases of aprotinin-induced anaphylaxis were reported in 61 publications. Eleven patients died. The reexposure interval was less than 3 months in 72% (38 of 53 patients). This review looks at t...    »
 
Zeitschriftentitel:
Ann Thorac Surg 
Jahr:
2005 
Band / Volume:
79 
Heft / Issue:
Seitenangaben Beitrag:
741-748 
Sprache:
eng 
Print-ISSN:
0003-4975 
TUM Einrichtung:
sthesiologie