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Dokumenttyp:
journal article 
Autor(en):
Ganea, K; Menke, A; Schmidt, MV; Lucae, S; Rammes, G; Liebl, C; Harbich, D; Sterlemann, V; Storch, C; Uhr, M; Holsboer, F; Binder, EB; Sillaber, I; Müller, MB 
Titel:
Convergent animal and human evidence suggests the activin/inhibin pathway to be involved in antidepressant response. 
Abstract:
Despite the overt need for improved treatment modalities in depression, efforts to develop conceptually novel antidepressants have been relatively unsuccessful so far. Here we present a translational approach combining results from hypothesis-free animal experiments with data from a genetic association study in depression. Comparing genes regulated by chronic paroxetine treatment in the mouse hippocampus with genes showing nominally significant association with antidepressant treatment response...    »
 
Zeitschriftentitel:
Transl Psychiatry 
Jahr:
2012 
Band / Volume:
Seitenangaben Beitrag:
e177 
Sprache:
eng 
TUM Einrichtung:
sthesiologie