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Document type:
journal article 
Author(s):
Sprenger, T; Valet, M; Woltmann, R; Zimmer, C; Freynhagen, R; Kochs, EF; Tölle, TR; Wagner, KJ 
Title:
Imaging pain modulation by subanesthetic s-(+)-ketamine. 
Abstract:
Little is known about the effects of low-dose S-(+)-ketamine on the cerebral processing of pain. We investigated the effects of subanesthetic IV S-(+)-ketamine doses on the perception of experimental painful heat stimuli. Healthy volunteers were evaluated with functional magnetic resonance imaging (fMRI) while receiving the painful stimuli in conjunction with placebo and increasing doses (0.05, 0.1, 0.15 mg x kg(-1) x h(-1)) of ketamine infusion. Vital variables were monitored and all subjects r...    »
 
Journal title abbreviation:
Anesth Analg 
Year:
2006 
Journal volume:
103 
Journal issue:
Pages contribution:
729-37 
Language:
eng 
Print-ISSN:
0003-2999 
TUM Institution:
Neurologische Klinik und Poliklinik; r Neuroradiologie; sthesiologie