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Document type:
journal article 
Author(s):
Rummel, C; Voss, T; Matsumura, K; Korte, S; Gerstberger, R; Roth, J; Hübschle, T 
Title:
Nuclear STAT3 translocation in guinea pig and rat brain endothelium during systemic challenge with lipopolysaccharide and interleukin-6. 
Abstract:
During systemic inflammation, cytokines are released by immune-competent cells into the circulation, which in turn signal the brain to mediate brain-controlled signs of illness. Cytokine-responsive brain cells can be mapped by histological analysis of cytokine-induced transcription factors or transcription factor-associated molecules revealing different cell phenotypes that respond to activation of the immune system. Critical sites mediating cytokine-dependent immuneffector functions can be divi...    »
 
Journal title abbreviation:
J Comp Neurol 
Year:
2005 
Journal volume:
491 
Journal issue:
Pages contribution:
1-14 
Language:
eng 
Print-ISSN:
0021-9967 
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie