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Dokumenttyp:
journal article 
Autor(en):
Haseneder, R; Kurz, J; Dodt, HU; Kochs, E; Zieglgänsberger, W; Scheller, M; Rammes, G; Hapfelmeier, G 
Titel:
Isoflurane reduces glutamatergic transmission in neurons in the spinal cord superficial dorsal horn: evidence for a presynaptic site of an analgesic action. 
Abstract:
The minimum alveolar concentration (MAC) of a volatile anesthetic defines anesthetic potency in terms of a suppressed motor response to a noxious stimulus. Therefore, the MAC of an anesthetic might in part reflect depression of motor neuron excitability. In the present study we evaluated the effect of isoflurane (ISO) on neurons in the substantia gelatinosa driven synaptically by putative nociceptive inputs in an in vitro spinal cord preparation of the rat. Whole-cell patch-clamp recordings were...    »
 
Zeitschriftentitel:
Anesth Analg 
Jahr:
2004 
Band / Volume:
98 
Heft / Issue:
Seitenangaben Beitrag:
1718-23, table of content 
Sprache:
eng 
Print-ISSN:
0003-2999 
TUM Einrichtung:
sthesiologie