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Dokumenttyp:
journal article 
Autor(en):
Fink, H; Yasuhara, S; Blobner, M; Martyn, JA 
Titel:
Up-regulation of acetylcholine receptors during subchronic infusion of pancuronium is caused by a posttranscriptional mechanism related to disuse. 
Abstract:
OBJECTIVE: Contrasting with the classic theory that competitive block of the acetylcholine receptor induces up-regulation of the receptor, recent studies show that irreversible block of acetylcholine receptors with alpha-bungarotoxin decreases acetylcholine receptor number within hours. This study investigated the early effects of competitive acetylcholine receptor block with the reversible, competitive muscle relaxant, pancuronium. DESIGN: Prospective, randomized, placebo-controlled experimenta...    »
 
Zeitschriftentitel:
Crit Care Med 
Jahr:
2004 
Band / Volume:
32 
Heft / Issue:
Seitenangaben Beitrag:
509-13 
Sprache:
eng 
Print-ISSN:
0090-3493 
TUM Einrichtung:
sthesiologie