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Document type:
journal article 
Author(s):
Nüssler, NC; Müller, AR; Weidenbach, H; Vergopoulos, A; Platz, KP; Volk, HD; Neuhaus, P; Nussler, AK 
Title:
IL-10 increases tissue injury after selective intestinal ischemia/reperfusion. 
Abstract:
OBJECTIVE This study focused on the effect of immunoregulatory cytokines on tissue injury after intestinal ischemia/reperfusion (IR). Furthermore, the role of nitric oxide, heme oxygenase-1 (HO-1) and the transcription factor NF-kappaB/Rel in the disease process was evaluated.SUMMARY BACKGROUND DATA Oxidative stress and inflammatory gene products contribute to ischemia/reperfusion injury (IRI). However, expression of stress proteins such as the inducible nitric oxide synthase (NOS-2) and HO-1 mi...    »
 
Journal title abbreviation:
Ann Surg 
Year:
2003 
Journal volume:
238 
Journal issue:
Pages contribution:
49-58 
Language:
eng 
Print-ISSN:
0003-4932 
TUM Institution:
II. Medizinische Klinik und Poliklinik