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Dokumenttyp:
journal article 
Autor(en):
Almlöf, Jonas Carlsson; Lundmark, Per; Lundmark, Anders; Ge, Bing; Pastinen, Tomi; Cardiogenics Consortium; Goodall, Alison H; Cambien, François; Deloukas, Panos; Ouwehand, Willem H; Syvänen, Ann-Christine; Schunkert, Heribert; Attwood, Tony; Belz, Stephanie; Braund, Peter; Brocheton, Jessy; Cooper, Jason; Crisp-Hihn, Abi; Diemert, Patrick; Erdmann, Jeanette; Foad, Nicola; Godefroy, Tiphaine; Gracey, Jay; Gray, Emma; Gwilliams, Rhian; Heimerl, Susanne; Hengstenberg, Christian; Jolley, Jennifer;...    »
 
Titel:
Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes. 
Abstract:
We applied genome-wide allele-specific expression analysis of monocytes from 188 samples. Monocytes were purified from white blood cells of healthy blood donors to detect cis-acting genetic variation that regulates the expression of long non-coding RNAs. We analysed 8929 regions harboring genes for potential long non-coding RNA that were retrieved from data from the ENCODE project. Of these regions, 60% were annotated as intergenic, which implies that they do not overlap with protein-coding gene...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2014 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e102612 
Sprache:
eng 
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen