Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Mosconi, Ilaria; Dubey, Lalit Kumar; Volpe, Beatrice; Esser-von Bieren, Julia; Zaiss, Mario M; Lebon, Luc; Massacand, Joanna C; Harris, Nicola L 
Titel:
Parasite Proximity Drives the Expansion of Regulatory T Cells in Peyer's Patches following Intestinal Helminth Infection. 
Abstract:
Helminth infections are typically chronic in nature; however, the exact molecular mechanisms by which these parasites promote or thwart host immunity remain unclear. Worm expulsion requires the differentiation of CD4(+) T cells into Th2 cells, while regulatory T cells (Tregs) act to dampen the extent of the Th2 response. Priming of T cells requires drainage or capture of antigens within lymphoid tissues, and in the case of intestinal helminths, such sites include the mucosa-associated Peyer's p...    »
 
Zeitschriftentitel:
Infect Immun 
Jahr:
2015 
Band / Volume:
83 
Heft / Issue:
Seitenangaben Beitrag:
3657-65 
Sprache:
eng 
Print-ISSN:
0019-9567 
TUM Einrichtung:
Institut für Molekulare Allergologie und Umweltforschung