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Document type:
journal article 
Author(s):
Albrecht, Eva; Sillanpää, Elina; Karrasch, Stefan; Alves, Alexessander Couto; Codd, Veryan; Hovatta, Iiris; Buxton, Jessica L; Nelson, Christopher P; Broer, Linda; Hägg, Sara; Mangino, Massimo; Willemsen, Gonneke; Surakka, Ida; Ferreira, Manuel A R; Amin, Najaf; Oostra, Ben A; Bäckmand, Heli M; Peltonen, Markku; Sarna, Seppo; Rantanen, Taina; Sipilä, Sarianna; Korhonen, Tellervo; Madden, Pamela A F; Gieger, Christian; Jörres, Rudolf A; Heinrich, Joachim; Behr, Jürgen; Huber, Rudolf M; Peters, An...    »
 
Title:
Telomere length in circulating leukocytes is associated with lung function and disease. 
Abstract:
Several clinical studies suggest the involvement of premature ageing processes in chronic obstructive pulmonary disease (COPD). Using an epidemiological approach, we studied whether accelerated ageing indicated by telomere length, a marker of biological age, is associated with COPD and asthma, and whether intrinsic age-related processes contribute to the interindividual variability of lung function. Our meta-analysis of 14 studies included 934 COPD cases with 15 846 controls defined according to...    »
 
Journal title abbreviation:
Eur Respir J 
Year:
2014 
Journal volume:
43 
Journal issue:
Pages contribution:
983-92 
Language:
eng 
Print-ISSN:
0903-1936 
TUM Institution:
Institut für Allgemeinmedizin