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Document type:
journal article 
Author(s):
Mäkinen, Ville-Petteri; Civelek, Mete; Meng, Qingying; Zhang, Bin; Zhu, Jun; Levian, Candace; Huan, Tianxiao; Segrè, Ayellet V; Ghosh, Sujoy; Vivar, Juan; Nikpay, Majid; Stewart, Alexandre F R; Nelson, Christopher P; Willenborg, Christina; Erdmann, Jeanette; Blakenberg, Stefan; O'Donnell, Christopher J; März, Winfried; Laaksonen, Reijo; Epstein, Stephen E; Kathiresan, Sekar; Shah, Svati H; Hazen, Stanley L; Reilly, Muredach P; Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CA...    »
 
Title:
Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease. 
Abstract:
The majority of the heritability of coronary artery disease (CAD) remains unexplained, despite recent successes of genome-wide association studies (GWAS) in identifying novel susceptibility loci. Integrating functional genomic data from a variety of sources with a large-scale meta-analysis of CAD GWAS may facilitate the identification of novel biological processes and genes involved in CAD, as well as clarify the causal relationships of established processes. Towards this end, we integrated 14 G...    »
 
Journal title abbreviation:
PLoS Genet 
Year:
2014 
Journal volume:
10 
Journal issue:
Pages contribution:
e1004502 
Language:
eng 
Print-ISSN:
1553-7390 
TUM Institution:
Klinik für Herz- und Kreislauferkrankungen