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Document type:
journal article 
Author(s):
Derycke, Lara; Eyerich, Stefanie; Van Crombruggen, Koen; Pérez-Novo, Claudina; Holtappels, Gabriele; Deruyck, Natalie; Gevaert, Philippe; Bachert, Claus 
Title:
Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps. 
Abstract:
In chronic rhinosinusitis (CRS) different phenotypes have been reported based on cytokine profile and inflammatory cell patterns. The aim of this study was to characterize the intracytoplasmatic cytokines of T cells infiltrating the inflamed sinonasal mucosa.Infiltrated T cells and tissue homogenates from sinonasal mucosal samples of 7 healthy subjects, 9 patients with CRS without nasal polyp (CRSsNP), 15 with CRS with nasal polyps (CRSwNP) and 5 cystic fibrosis patients (CF-NP) were analyzed fo...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2014 
Journal volume:
Journal issue:
Pages contribution:
e97581 
Language:
eng 
TUM Institution:
Institut für Molekulare Allergologie und Umweltforschung