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Document type:
journal article 
Author(s):
Schaumann, Frank; Frömke, Cornelia; Dijkstra, Dorothea; Alessandrini, Francesca; Windt, Horst; Karg, Erwin; Müller, Meike; Winkler, Carla; Braun, Armin; Koch, Armin; Hohlfeld, Jens; Behrendt, Heidrun; Schmid, Otmar; Koch, Wolfgang; Schulz, Holger; Krug, Norbert 
Title:
Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: results of a double-blinded randomized cross-over clinical pilot study. 
Abstract:
Epidemiological and experimental studies suggest that exposure to ultrafine particles (UFP) might aggravate the allergic inflammation of the lung in asthmatics.We exposed 12 allergic asthmatics in two subgroups in a double-blinded randomized cross-over design, first to freshly generated ultrafine carbon particles (64 ?g/m(3); 6.1 ± 0.4 × 10(5) particles/cm(3) for 2 h) and then to filtered air or vice versa with a 28-day recovery period in-between. Eighteen hours after each exposure, grass polle...    »
 
Journal title abbreviation:
Part Fibre Toxicol 
Year:
2014 
Journal volume:
11 
Pages contribution:
39 
Language:
eng 
TUM Institution:
Institut für Molekulare Allergologie und Umweltforschung