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Document type:
Buchbeitrag 
Author(s):
Pérez-Velázquez, Judith; Gevertz, Jana L.; Karolak, Aleksandra; Rejniak, Katarzyna A. 
Title:
Microenvironmental Niches and Sanctuaries: A Route to Acquired Resistance 
Pages contribution:
149--164 
Abstract:
A tumor vasculature that is functionally abnormal results in irregular gradients of metabolites and drugs within the tumor tissue. Recently, significant efforts have been committed to experimentally examine how cellular response to anti-cancer treatments varies based on the environment in which the cells are grown. In vitro studies point to specific conditions in which tumor cells can remain dormant and survive the treatment. In vivo results suggest that cells can escape the effects of drug ther...    »
 
Editor:
Rejniak, Katarzyna A. 
Book title:
Systems Biology of Tumor Microenvironment: Quantitative Modeling and Simulations 
Publisher:
Springer International Publishing 
Publisher address:
Cham 
Year:
2016 
Print-ISBN:
978-3-319-42023-3